Description

2-Hydrazinocarbonyl-Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester CAS NO 359803-43-3 is a high-purity, protected pyrrolidine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its dual functional groups—a protected carboxylic acid and a reactive hydrazine moiety—which enable precise molecular construction for complex targets. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of drug candidates, particularly those containing pyrrolidine scaffolds for protease inhibitors or neurological agents.
• Peptidomimetic Research: Used to introduce constrained pyrrolidine rings and hydrazide linkages into peptide analogs to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides and fungicides with specific mode-of-action targets.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes and molecular tags for studying enzyme function.
• Ligand Development for Catalysis: Utilized to create novel chiral ligands and organocatalysts for asymmetric synthesis applications.
• Custom Fine Chemical Production: A versatile starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds.

Basic Information

Product Name	2-Hydrazinocarbonyl-Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	359803-43-3
Molecular Formula	C10H19N3O3
Molecular Weight	229.28 g/mol
Synonyms	1-Boc-2-(hydrazinecarbonyl)pyrrolidine; 1-(tert-Butoxycarbonyl)-2-(hydrazinecarbonyl)pyrrolidine; tert-Butyl 2-(hydrazinecarbonyl)pyrrolidine-1-carboxylate; 2-(Hydrazinecarbonyl)-1-pyrrolidinecarboxylic Acid 1,1-Dimethylethyl Ester; Pyrrolidine-1-carboxylic acid, 2-(hydrazinecarbonyl)-, 1,1-dimethylethyl ester; Boc-Pyrrolidine-2-carbohydrazide
EINECS	Contact for details

Quality Control

Our 2-Hydrazinocarbonyl-Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed chromatographic data are provided for each lot to support your R&D and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture and oxidation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.