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Quinoline-5-Boronic Acid CAS NO 355386-94-6
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CAS No.:355386-94-6
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Quinoline-5-Boronic Acid CAS NO 355386-94-6 is a high-value boronic acid derivative and a key synthetic building block in modern organic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing active pharmaceutical ingredients (APIs), functional ligands, and organic electronic materials.
Application
- Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those containing quinoline scaffolds for oncology, antiviral, and anti-inflammatory applications.
- Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides with improved efficacy and selectivity.
- Material Science: Serves as a building block for organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and other functional organic electronic materials.
- Chemical Research & Development: A versatile reagent for constructing complex molecular architectures in medicinal chemistry and catalyst ligand development.
- Fine Chemical Production: Employed in the custom synthesis of specialty chemicals and complex organic molecules for various industrial applications.
Basic Information
| Product Name | Quinoline-5-Boronic Acid |
| CAS No. | 355386-94-6 |
| Molecular Formula | C9H8BNO2 |
| Molecular Weight | 172.98 g/mol |
| Synonyms | 5-Quinolineboronic Acid; (Quinolin-5-yl)boronic Acid; Quinoline-5-boronic Acid Pinacol Ester (common precursor); B-(5-Quinolinyl)boronic Acid; 5-Boronquinoline; 5-Quinolylboronic Acid |
| EINECS | Contact for details |
Quality Control
Our Quinoline-5-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and reliability for your critical processes.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (argon or nitrogen) for long-term storage to maintain stability and purity.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥97.0% (Typical 98-99%) |
| Water Content (KF) | ≤1.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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