Description

6-Amino-4-(2,6-Difluorophenyl)-3-Methyl-1-Phenyl-1,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile CAS NO 354554-71-5 is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyranopyrazole chemical class. This compound is valued for its complex heterocyclic structure, which serves as a critical building block in modern medicinal chemistry. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of new drug candidates, particularly in therapeutic areas targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, leveraging its difluorophenyl and pyranopyrazole motifs for bioactivity.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme inhibition and protein-ligand interactions in academic and industrial research settings.
• Material Science Research: Investigated as a potential precursor for specialty chemicals and functional materials due to its unique fused-ring architecture.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.

Basic Information

Product Name	6-Amino-4-(2,6-Difluorophenyl)-3-Methyl-1-Phenyl-1,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile
CAS No.	354554-71-5
Molecular Formula	C20H14F2N4O
Molecular Weight	364.35 g/mol
Synonyms	6-Amino-4-(2,6-difluorophenyl)-3-methyl-1-phenyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile; 1,4-Dihydropyrano[2,3-c]pyrazole-5-carbonitrile, 6-amino-4-(2,6-difluorophenyl)-3-methyl-1-phenyl-; 354554-71-5; Pyranopyrazole Carbonitrile Derivative; Difluorophenyl Pyranopyrazole; API Intermediate 354554-71-5
EINECS	Contact for details

Quality Control

Our 6-Amino-4-(2,6-Difluorophenyl)-3-Methyl-1-Phenyl-1,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.