Description

6-Amino-3-(tert-Butyl)-4-(4-Quinolinyl)-2,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile CAS NO 354554-66-8 is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyranopyrazole chemical class. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel therapeutic agents with targeted biological activity. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, particularly in oncology and anti-inflammatory research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates targeting specific enzymes or receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic areas.
• Oncology Drug Development: Serves as a core scaffold for developing potential kinase inhibitors and other anti-cancer agents.
• Anti-inflammatory Agent Synthesis: Employed in the research and development of new compounds with potential anti-inflammatory properties.
• Chemical Biology Probes: Utilized to create specialized molecular probes for studying biological pathways and protein functions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical innovation pipelines.

Basic Information

Product Name	6-Amino-3-(tert-Butyl)-4-(4-Quinolinyl)-2,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile
CAS No.	354554-66-8
Molecular Formula	C₂₀H₁₉N₅O
Molecular Weight	345.40 g/mol
Synonyms	6-Amino-3-tert-butyl-4-(quinolin-4-yl)-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile; 6-Amino-3-(1,1-dimethylethyl)-4-(4-quinolinyl)-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile; 354554-66-8; Pyrano[2,3-c]pyrazole-5-carbonitrile, 6-amino-3-(1,1-dimethylethyl)-4-(4-quinolinyl)-2,4-dihydro-; tert-Butyl pyranopyrazole carbonitrile derivative; 4-Quinolinyl pyranopyrazole intermediate
EINECS	Contact for details

Quality Control

Our 6-Amino-3-(tert-Butyl)-4-(4-Quinolinyl)-2,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.