Description

7-Chloro-3-[(4-Ethyl-5-Phenyl-4H-1,2,4-Triazol-3-Yl)Sulfanyl]-4-Phenyl-2-Quinolinol is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound matters because it serves as a critical building block for research and development in medicinal chemistry, particularly for creating molecules with potential therapeutic activity. Pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers need this precise intermediate to develop new drugs and high-value chemical products. Its unique molecular architecture, combining quinoline and triazole pharmacophores, makes it a valuable scaffold for targeted drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting various diseases.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• Agrochemical Development: Serves as an intermediate for creating new crop protection agents and pesticides.
• Biochemical Research: Potential use as a tool compound or probe in biochemical assays and target validation.
• Material Science: Exploration into organic electronic materials or metal-organic frameworks (MOFs) due to its conjugated system.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.

Basic Information

Product Name	7-Chloro-3-[(4-Ethyl-5-Phenyl-4H-1,2,4-Triazol-3-Yl)Sulfanyl]-4-Phenyl-2-Quinolinol
CAS No.	354538-40-2
Molecular Formula	C25H17ClN4OS
Molecular Weight	456.95 g/mol
Synonyms	7-Chloro-3-[(4-ethyl-5-phenyl-4H-1,2,4-triazol-3-yl)thio]-4-phenyl-2-quinolinol; 7-Chloro-3-((4-ethyl-5-phenyl-4H-1,2,4-triazol-3-yl)thio)-4-phenylquinolin-2-ol; 2-Quinolinol, 7-chloro-3-[(4-ethyl-5-phenyl-4H-1,2,4-triazol-3-yl)thio]-4-phenyl-; 354538-40-2; 7-Chloro-3-((4-ethyl-5-phenyl-4H-1,2,4-triazol-3-yl)sulfanyl)-4-phenylquinolin-2-ol
EINECS	Contact for details

Quality Control

Our 7-Chloro-3-[(4-Ethyl-5-Phenyl-4H-1,2,4-Triazol-3-Yl)Sulfanyl]-4-Phenyl-2-Quinolinol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure compliance with ICH guidelines. A comprehensive Certificate of Analysis (COA) detailing all test results and specifications is provided with each shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and easily oxidized; prolonged exposure to air, light, or moisture should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.