Description

3-(2-Methylprop-2-En-1-Yl)-2-(Methylsulfanyl)-3H-Spiro[Benzo[H]Quinazoline-5,1'-Cyclohexan]-4(6H)-One is a sophisticated spirocyclic quinazolinone derivative, a key synthetic intermediate designed for advanced pharmaceutical and agrochemical research. Its complex molecular architecture, featuring a spiro junction and a reactive methylsulfanyl group, makes it a valuable building block for constructing novel bioactive compounds. This high-purity intermediate is essential for medicinal chemists and R&D teams in the pharmaceutical, agrochemical, and fine chemical sectors seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used as a key scaffold for developing new generations of herbicides, fungicides, and insecticides with novel modes of action.
• Chemical Biology Probe Development: Utilized in creating specialized molecular probes for studying enzyme inhibition and protein-ligand interactions.
• Material Science Research: Investigated as a monomer or additive for creating advanced polymers with specific optical or electronic properties.
• Academic & Contract Research: Supplied to universities and CROs (Contract Research Organizations) for exploratory synthetic chemistry and methodology development.
• Custom Synthesis Building Block: Provided for bespoke synthesis projects requiring complex, functionalized heterocyclic structures.

Basic Information

Item	Details
Product Name	3-(2-Methylprop-2-En-1-Yl)-2-(Methylsulfanyl)-3H-Spiro[Benzo[H]Quinazoline-5,1'-Cyclohexan]-4(6H)-One
CAS No.	353762-13-7
Molecular Formula	C22H26N2OS
Molecular Weight	366.52 g/mol
Synonyms	2-(Methylthio)-3-(2-methyl-2-propen-1-yl)-3H-spiro[benzo[h]quinazoline-5,1'-cyclohexan]-4(6H)-one; 3-(2-Methylallyl)-2-(methylsulfanyl)-3H-spiro[benzo[h]quinazoline-5,1'-cyclohexane]-4(6H)-one; Spiro[benzo[h]quinazoline-5,1'-cyclohexane]-4(6H)-one, 3-(2-methyl-2-propen-1-yl)-2-(methylthio)-; CAS 353762-13-7
EINECS	Contact for details

Quality Control

Our production of 3-(2-Methylprop-2-En-1-Yl)-2-(Methylsulfanyl)-3H-Spiro[Benzo[H]Quinazoline-5,1'-Cyclohexan]-4(6H)-One adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and MS for identity verification. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all critical quality attributes to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.