Description

2-Methyl-5-(Pyrrolidine-1-Sulfonyl)Benzoic Acid is a high-purity, synthetically valuable benzoic acid derivative featuring a pyrrolidine sulfonamide moiety. This compound serves as a critical pharmaceutical intermediate and custom synthesis building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate its unique sulfonamide-substituted aromatic structure into novel active molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those targeting enzymes where the sulfonamide group acts as a pharmacophore.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies for developing new therapeutic agents.
• Custom Synthesis & Contract Manufacturing: Serves as a specialized starting material or reagent for the custom synthesis of complex organic molecules on a commercial scale.
• Agrochemical Research: Intermediate in the development of new herbicides, fungicides, or insecticides that utilize sulfonamide chemistry.
• Chemical Biology Probes: Can be used to create molecular probes for studying biological pathways and protein function.
• Material Science: Potential monomer or additive for creating specialized polymers with specific functional properties.

Basic Information

Item	Detail
Product Name	2-Methyl-5-(Pyrrolidine-1-Sulfonyl)Benzoic Acid
CAS No.	353467-90-0
Molecular Formula	C₁₃H₁₇NO₄S
Molecular Weight	283.34 g/mol
Synonyms	5-(Pyrrolidine-1-sulfonyl)-2-methylbenzoic acid; 2-Methyl-5-(1-pyrrolidinylsulfonyl)benzoic acid; Benzoic acid, 2-methyl-5-(1-pyrrolidinylsulfonyl)-; 353467-90-0; 2-Methyl-5-(pyrrolidine-1-sulfonyl)benzoic acid; 2-Methyl-5-(N-pyrrolidinosulfonyl)benzoic acid
EINECS	Contact for details

Quality Control

Our 2-Methyl-5-(Pyrrolidine-1-Sulfonyl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and structural identity, meeting the stringent requirements for research and development applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.