Description

2-Propanamine,1-[(6-Fluoro-3-Pyridinyl)Oxy]-N,n-Dimethyl-,(2R)-(9Ci) is a high-purity, stereochemically defined chiral amine derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its core value lies in enabling the precise construction of complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require a reliable source of high-quality, structurally complex building blocks.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Intermediate in the production of advanced pesticides and herbicides, where the fluoropyridinyl moiety contributes to biological activity.
• Ligand and Catalyst Development: Used in the research and preparation of chiral ligands for asymmetric catalysis.
• Chemical Research (R&D): A versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies in academic and industrial laboratories.
• Process Chemistry: Serves as a defined starting material or intermediate in scale-up and optimization of synthetic routes for commercial production.

Basic Information

Product Name	2-Propanamine,1-[(6-Fluoro-3-Pyridinyl)Oxy]-N,n-Dimethyl-,(2R)-(9Ci)
CAS No.	352707-32-5
Molecular Formula	C10H15FN2O
Molecular Weight	198.24 g/mol
Synonyms	(2R)-1-[(6-Fluoro-3-pyridinyl)oxy]-N,N-dimethyl-2-propanamine; (R)-1-((6-Fluoropyridin-3-yl)oxy)-N,N-dimethylpropan-2-amine; 1-[(6-Fluoro-3-pyridinyl)oxy]-N,N-dimethyl-(2R)-2-propanamine; (R)-N,N-Dimethyl-1-((6-fluoropyridin-3-yl)oxy)propan-2-amine; (2R)-1-((6-Fluoropyridin-3-yl)oxy)-N,N-dimethylpropan-2-amine; 352707-32-5; (R)-Isomer of Fluopyram intermediate
EINECS	Contact for details

Quality Control

Our production of 2-Propanamine,1-[(6-Fluoro-3-Pyridinyl)Oxy]-N,n-Dimethyl-,(2R)-(9Ci) adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets exacting standards for research and process use. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment. We support compliance with cGMP and ICH guidelines where required for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids and strong oxidizing agents. Due to its fluoride/strong alkali nature, ensure containers are kept tightly sealed to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (R-Isomer)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.