Description

Ethyl 5-Fluoroquinoline-3-Carboxylate is a high-purity fluorinated quinoline derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of new chemical entities and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting infectious diseases and central nervous system disorders.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging the fluorinated quinoline core for enhanced biological activity.
• Material Science Research: Employed in the synthesis of organic semiconductors, ligands for metal-organic frameworks (MOFs), and other functional materials.
• Chemical Biology Probes: Serves as a fluorescent tag or a core structure for developing molecular probes to study biological processes.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	Ethyl 5-Fluoroquinoline-3-Carboxylate
CAS No.	352521-49-4
Molecular Formula	C₁₂H₁₀FNO₂
Molecular Weight	219.21 g/mol
Synonyms	5-Fluoroquinoline-3-carboxylic acid ethyl ester; Ethyl 5-fluoro-3-quinolinecarboxylate; 3-Quinolinecarboxylic acid, 5-fluoro-, ethyl ester; 5-Fluoro-3-quinolinecarboxylic acid ethyl ester; Ethyl 5-fluoroquinoline-3-carboxylate; 352521-49-4; 5-Fluoroquinoline-3-carboxylate ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-Fluoroquinoline-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.