Description

5-Chloroquinoline-3-Carboxylic Acid Ethyl Ester is a high-purity, versatile organic building block essential for advanced chemical synthesis. This compound serves as a critical intermediate in the development of complex molecules, particularly within the pharmaceutical and agrochemical sectors. It is primarily sought after by research institutions and industrial manufacturers for constructing novel quinoline-based compounds, where its specific chlorinated and esterified structure enables precise molecular modifications.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds with quinoline scaffolds.
• Agrochemical Research: Used in developing new herbicides, fungicides, and insecticides that require halogenated quinoline structures.
• Material Science: Serves as a monomer or functionalizing agent for creating specialized polymers and organic electronic materials.
• Dye and Pigment Synthesis: Intermediate for producing complex heterocyclic dyes and colorants.
• Ligand and Catalyst Development: Building block for synthesizing novel chelating ligands and organocatalysts used in asymmetric synthesis.
• Academic and R&D: Fundamental research reagent for exploring new organic reactions and heterocyclic chemistry.

Basic Information

Product Name	5-Chloroquinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	352521-48-3
Molecular Formula	C₁₂H₁₀ClNO₂
Molecular Weight	235.67 g/mol
Synonyms	Ethyl 5-Chloroquinoline-3-carboxylate; 5-Chloro-3-quinolinecarboxylic Acid Ethyl Ester; 3-Carbethoxy-5-chloroquinoline; 5-Chloroquinoline-3-carboxylic Acid Ethyl Ester; Ethyl 5-chloro-3-quinolinecarboxylate; 352521-48-3; 5-Chloro-quinoline-3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 5-Chloroquinoline-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong alkalis and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.