Description

3-Amino-5,6,7,8-Tetrahydrothieno[2,3-B]Quinoline-2-Carboxylic Acid is a high-purity, heterocyclic organic compound with the CAS registry number 352454-15-0. This advanced pharmaceutical intermediate is critical for the synthesis of complex molecules, offering a unique fused-ring scaffold for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for creating novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Synthesis: Used in the preparation of more complex heterocyclic compounds and fused-ring systems for specialized chemical libraries.
• Bioconjugation & Probe Development: The carboxylic acid and amino functional groups allow for derivatization to create biochemical probes and labeled compounds.
• Academic & Industrial R&D: Essential material for research institutions and CROs (Contract Research Organizations) focused on developing new chemical entities.

Basic Information

Product Name	3-Amino-5,6,7,8-Tetrahydrothieno[2,3-B]Quinoline-2-Carboxylic Acid
CAS No.	352454-15-0
Molecular Formula	C12H12N2O2S
Molecular Weight	248.30 g/mol
Synonyms	3-Aminothieno[2,3-b]quinoline-2-carboxylic acid, 5,6,7,8-tetrahydro-; 2-Carboxy-3-amino-5,6,7,8-tetrahydrothieno[2,3-b]quinoline; 3-Amino-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxylic acid; Tetrahydrothienoquinoline carboxylic acid derivative; CAS 352454-15-0; Thienoquinoline intermediate; ATCQ-2-COOH
EINECS	Contact for details

Quality Control

Our production of 3-Amino-5,6,7,8-Tetrahydrothieno[2,3-B]Quinoline-2-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, related substances, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.