Description

4-[(Furan-2-Ylmethyl)-Carbamoyl]-1,2,2-Trimethyl-Spiro[2.3]Hexane-1-Carboxylic Acid CAS NO 352452-38-1 is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic and furan-containing molecular architecture. This compound is of significant commercial interest for its role in the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex, three-dimensional molecular scaffolds. It is primarily targeted at pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and process development.

Application

• Key intermediate in the synthesis of novel Active Pharmaceutical Ingredients (APIs) with spirocyclic structures.
• Building block for medicinal chemistry research, enabling the exploration of new chemical space for drug discovery.
• Precursor in the development of specialty fine chemicals and complex organic molecules.
• Used in process chemistry and scale-up studies for pharmaceutical manufacturing.
• Potential intermediate for agrochemicals requiring specific steric and electronic properties.
• Reference standard for analytical method development and quality control in pharmaceutical production.

Basic Information

Product Name	4-[(Furan-2-Ylmethyl)-Carbamoyl]-1,2,2-Trimethyl-Spiro[2.3]Hexane-1-Carboxylic Acid
CAS No.	352452-38-1
Molecular Formula	C17H23NO4
Molecular Weight	305.37 g/mol
Synonyms	4-[(Furan-2-ylmethyl)carbamoyl]-1,2,2-trimethylspiro[2.3]hexane-1-carboxylic acid; 1,2,2-Trimethyl-4-[[(2-furanylmethyl)amino]carbonyl]spiro[2.3]hexane-1-carboxylic acid; Spiro[2.3]hexane-1-carboxylic acid, 4-[(2-furanylmethyl)carbamoyl]-1,2,2-trimethyl-; 352452-38-1; Furan-2-ylmethyl-carbamic acid (1,2,2-trimethyl-spiro[2.3]hexan-4-yl) ester (tautomeric form); Advanced Spirocyclic Intermediate
EINECS	Contact for details

Quality Control

Our production of 4-[(Furan-2-Ylmethyl)-Carbamoyl]-1,2,2-Trimethyl-Spiro[2.3]Hexane-1-Carboxylic Acid adheres to stringent quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are available upon request. We support compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.