Description

5-Chloro-4-Hydroxy-8-Methylquinoline-3-Carboxylic Acid Ethyl Ester is a high-purity, synthetically valuable quinoline derivative. This compound serves as a critical advanced pharmaceutical intermediate for the development of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex heterocyclic molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly in antimicrobial and anti-inflammatory research.
• Organic Synthesis Reagent: Used in the construction of complex quinoline-based molecular frameworks for material science and agrochemical research.
• Chemical Research & Development: Employed as a standard or starting material in academic and industrial R&D for method development and structure-activity relationship (SAR) studies.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	5-Chloro-4-Hydroxy-8-Methylquinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	351893-52-2
Molecular Formula	C₁₄H₁₂ClNO₃
Molecular Weight	277.70 g/mol
Synonyms	Ethyl 5-Chloro-4-hydroxy-8-methylquinoline-3-carboxylate; 5-Chloro-4-hydroxy-8-methyl-3-quinolinecarboxylic Acid Ethyl Ester; 8-Methyl-5-chloro-4-hydroxyquinoline-3-carboxylic Acid Ethyl Ester; 351893-52-2; Quinoline-3-carboxylic acid, 5-chloro-4-hydroxy-8-methyl-, ethyl ester
EINECS	Contact for details

Quality Control

Our 5-Chloro-4-Hydroxy-8-Methylquinoline-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.