Description

n-[2-Chloro-5-(Trifluoromethyl)Phenyl]-N'-(4,6-Dimethylpyrimidin-2-Yl)Guanidine is a specialized guanidine derivative of significant interest in advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of high-performance agrochemicals and pharmaceuticals, where its unique trifluoromethyl and chlorophenyl moieties confer valuable biological activity. Industrial researchers and manufacturers in the agrochemical and pharmaceutical sectors need this high-purity intermediate to develop novel crop protection agents and active pharmaceutical ingredients (APIs).

Application

• Agrochemical Intermediate: A critical building block for the synthesis of novel fungicides, herbicides, and insecticides, leveraging its structural motifs for targeted activity.
• Pharmaceutical Research: Serves as a key scaffold in medicinal chemistry for developing new drug candidates, particularly in areas requiring guanidine-based pharmacophores.
• Chemical Synthesis: Used in organic synthesis as a versatile intermediate for constructing complex molecules containing pyrimidine and substituted phenyl groups.
• Crop Protection Formulations: Incorporated into the R&D and production of advanced formulations designed for efficacy and environmental compatibility.
• Biochemical Research: Employed in biochemical studies as a tool compound to investigate enzyme inhibition and receptor-ligand interactions.
• Material Science Precursor: Potential use in the synthesis of specialty chemicals and functional materials requiring specific halogenated aromatic structures.

Basic Information

Product Name	n-[2-Chloro-5-(Trifluoromethyl)Phenyl]-N'-(4,6-Dimethylpyrimidin-2-Yl)Guanidine
CAS No.	351468-83-2
Molecular Formula	C14H12ClF3N5
Molecular Weight	357.73 g/mol
Synonyms	2-Chloro-α,α,α-trifluoro-N-[imino(4,6-dimethyl-2-pyrimidinyl)amino]-p-toluidine; N-(2-Chloro-5-(trifluoromethyl)phenyl)-N'-(4,6-dimethylpyrimidin-2-yl)guanidine; Guanidine, N-[2-chloro-5-(trifluoromethyl)phenyl]-N'-(4,6-dimethyl-2-pyrimidinyl)-; 351468-83-2; AG-CN/095082; CTK8I7222; SCHEMBL23364077; ZINC000005099761
EINECS	Contact for details

Quality Control

Our production of n-[2-Chloro-5-(Trifluoromethyl)Phenyl]-N'-(4,6-Dimethylpyrimidin-2-Yl)Guanidine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. Our quality system is designed to support cGMP and ISO standards for industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent exposure to atmospheric humidity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.