Description

2-Chloro-7,8-Dihydro-6H-Cyclopenta[G]Quinoline-3-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its fused quinoline and cyclopentane structure. This compound is a critical building block in the synthesis of complex molecules, offering a versatile aldehyde functional group for further chemical elaboration. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Organic Synthesis Building Block: Used in research-scale and process chemistry for constructing fused polycyclic heterocyclic systems via its reactive aldehyde group.
• Agrochemical Research: Serves as a starting material for developing new active ingredients in crop protection and pest management products.
• Material Science: Investigated for the preparation of organic ligands and functional molecules with potential applications in catalysis or optoelectronics.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for methodological studies and novel compound library generation.

Basic Information

Product Name	2-Chloro-7,8-Dihydro-6H-Cyclopenta[G]Quinoline-3-Carbaldehyde
CAS No.	351365-89-4
Molecular Formula	C₁₃H₁₀ClNO
Molecular Weight	231.68 g/mol
Synonyms	2-Chloro-7,8-dihydro-6H-cyclopenta[g]quinoline-3-carboxaldehyde; 2-Chloro-6H-cyclopenta[g]quinoline-3-carbaldehyde, 7,8-dihydro-; 3-Formyl-2-chloro-7,8-dihydro-6H-cyclopenta[g]quinoline; 2-Chloro-7,8-dihydrocyclopenta[g]quinoline-3-carbaldehyde; CAS 351365-89-4
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-7,8-Dihydro-6H-Cyclopenta[G]Quinoline-3-Carbaldehyde is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for pharmaceutical R&D and scale-up. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the material under an inert atmosphere for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.