Description

6-Bromo-2-(3,4,5-Trimethoxy-Phenyl)-Quinoline-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in medicinal chemistry research and development, serving as a critical building block for the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of small molecule drugs, particularly those targeting kinase inhibition or other complex biological pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential drug candidates, especially in oncology and anti-inflammatory research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Kinase Inhibitor Development: The quinoline-carboxylic acid moiety makes it a valuable starting material for designing molecules that interact with ATP-binding sites of various kinases.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing organizations (CMOs) for producing specialized, high-value compounds for clinical trials.
• Biochemical Tool Compound: May be used to develop chemical probes for investigating specific biological mechanisms and pathways in academic and industrial settings.

Basic Information

Product Name	6-Bromo-2-(3,4,5-Trimethoxy-Phenyl)-Quinoline-4-Carboxylic Acid
CAS No.	351329-63-0
Molecular Formula	C19H16BrNO5
Molecular Weight	418.24 g/mol
Synonyms	6-Bromo-2-(3,4,5-trimethoxyphenyl)quinoline-4-carboxylic acid; 4-Quinolinecarboxylic acid, 6-bromo-2-(3,4,5-trimethoxyphenyl)-; 2-(3,4,5-Trimethoxyphenyl)-6-bromoquinoline-4-carboxylic acid; 6-Bromo-2-(3,4,5-trimethoxyphenyl)-4-quinolinecarboxylic acid; 351329-63-0; 6-Bromo-2-(3,4,5-trimethoxy-phenyl)-quinoline-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-(3,4,5-Trimethoxy-Phenyl)-Quinoline-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality commitment supports applications in cGMP environments and advanced research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from prolonged exposure and to prevent contamination.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.