Description

tert-Butyl 7-Amino-3,4-Dihydroquinoline-1(2H)-Carboxylate is a high-purity, protected amine derivative of the dihydroquinoline scaffold, serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile and reactive amine handle that is protected from unwanted side reactions, enabling the precise construction of complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic materials.
• Academic & Contract Research: A valuable reagent for methodology development, heterocyclic chemistry research, and library synthesis in academic and CRO (Contract Research Organization) settings.
• Peptidomimetics & Bio-conjugation: The protected amine group is instrumental in creating peptide analogs and for site-specific bioconjugation strategies.

Basic Information

Product Name	tert-Butyl 7-Amino-3,4-Dihydroquinoline-1(2H)-Carboxylate
CAS No.	351324-70-4
Molecular Formula	C₁₄H₁₈N₂O₂
Molecular Weight	246.31 g/mol
Synonyms	1-Boc-7-amino-1,2,3,4-tetrahydroquinoline; tert-Butyl 7-amino-3,4-dihydro-2H-quinoline-1-carboxylate; 7-Amino-1,2,3,4-tetrahydroquinoline-1-carboxylic acid tert-butyl ester; 1-N-Boc-7-amino-1,2,3,4-tetrahydroquinoline; 7-Amino-N-Boc-1,2,3,4-tetrahydroquinoline; Boc-7-ATQ; 351324-70-4
EINECS	Contact for details

Quality Control

Our tert-Butyl 7-Amino-3,4-Dihydroquinoline-1(2H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing specifications such as HPLC purity, NMR confirmation, and residual solvent levels are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.