Description

3-(4-Chlorophenyl)-6-Methoxy-4-Methylidene-3,4-Dihydroquinazolin-2(1H)-One is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing new drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel quinazolinone-based drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• API Development: Serves as a building block in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs) targeting various disease pathways.
• Biochemical Tool Compound: May be utilized in biochemical assays to study enzyme inhibition or receptor binding mechanisms.
• Academic Research: Employed in university and institutional labs for organic synthesis methodology development and heterocyclic chemistry studies.

Basic Information

Product Name	3-(4-Chlorophenyl)-6-Methoxy-4-Methylidene-3,4-Dihydroquinazolin-2(1H)-One
CAS No.	351225-57-5
Molecular Formula	C16H13ClN2O2
Molecular Weight	300.74 g/mol
Synonyms	3-(4-Chlorophenyl)-6-methoxy-4-methylidene-3,4-dihydro-2(1H)-quinazolinone; 4-(4-Chlorophenyl)-7-methoxy-1-methylidene-1,2,3,4-tetrahydroquinazolin-2-one; 351225-57-5; Quinazolin-2(1H)-one, 3-(4-chlorophenyl)-3,4-dihydro-6-methoxy-4-methylene-; 3-(p-Chlorophenyl)-6-methoxy-4-methylidene-3,4-dihydroquinazolin-2(1H)-one
EINECS	Contact for details

Quality Control

Our production of 3-(4-Chlorophenyl)-6-Methoxy-4-Methylidene-3,4-Dihydroquinazolin-2(1H)-One adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.