Description

4-(4-Chlorophenyl)-2,2,4-Trimethyl-1-[(4-Methylphenyl)Sulfonyl]-1,2,3,4-Tetrahydroquinoline is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical industries engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of new chemical entities (NCEs) and potential drug candidates.
• Organic Synthesis Building Block: Used in complex multi-step organic reactions, including cyclizations and functional group transformations, due to its reactive sulfonyl and tetrahydroquinoline groups.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies aimed at developing new therapies.
• Fine Chemical Production: Employed in the manufacture of specialized, high-value chemicals for agrochemical and material science applications.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process optimization for client projects.

Basic Information

Item	Detail
Product Name	4-(4-Chlorophenyl)-2,2,4-Trimethyl-1-[(4-Methylphenyl)Sulfonyl]-1,2,3,4-Tetrahydroquinoline
CAS No.	351191-62-3
Molecular Formula	C25H26ClNO2S
Molecular Weight	439.99 g/mol
Synonyms	1-[(4-Methylphenyl)sulfonyl]-4-(4-chlorophenyl)-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline; 4-(p-Chlorophenyl)-2,2,4-trimethyl-1-(p-tolylsulfonyl)-1,2,3,4-tetrahydroquinoline; 1-(4-Methylbenzenesulfonyl)-4-(4-chlorophenyl)-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline; 4-(4-Chlorophenyl)-2,2,4-trimethyl-1-tosyl-1,2,3,4-tetrahydroquinoline; CAS 351191-62-3
EINECS	Contact for details

Quality Control

Our 4-(4-Chlorophenyl)-2,2,4-Trimethyl-1-[(4-Methylphenyl)Sulfonyl]-1,2,3,4-Tetrahydroquinoline is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.