Description

n-[7-(4-Methoxyphenyl)-5-Oxo-5,6,7,8-Tetrahydro-2-Quinazolinyl]Acetamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value in the research and development of novel therapeutic agents, particularly as a key building block in medicinal chemistry. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of potential drug candidates, especially within oncology and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel, biologically active quinazoline derivatives for drug discovery programs.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Kinase Inhibitor Development: Its core structure is relevant for the research and development of potential kinase inhibitors, a major class of targeted cancer therapies.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling of related active pharmaceutical ingredients (APIs).
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.

Basic Information

Product Name	n-[7-(4-Methoxyphenyl)-5-Oxo-5,6,7,8-Tetrahydro-2-Quinazolinyl]Acetamide
CAS No.	351163-44-5
Molecular Formula	C₁₉H₁₉N₃O₃
Molecular Weight	337.37 g/mol
Synonyms	N-[7-(4-Methoxyphenyl)-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl]acetamide; 2-Acetamido-7-(4-methoxyphenyl)-5,6,7,8-tetrahydroquinazolin-5-one; Acetamide, N-[7-(4-methoxyphenyl)-5-oxo-5,6,7,8-tetrahydro-2-quinazolinyl]-; 351163-44-5; 7-(4-Methoxyphenyl)-2-acetamido-5,6,7,8-tetrahydroquinazolin-5-one
EINECS	Contact for details

Quality Control

Our n-[7-(4-Methoxyphenyl)-5-Oxo-5,6,7,8-Tetrahydro-2-Quinazolinyl]Acetamide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.