Description

6-Bromo-2-(5-Methylthiophen-2-Yl)Quinoline-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its distinct quinoline-thiophene hybrid structure. This compound matters for its critical role as a key building block in the synthesis of complex, biologically active molecules, particularly in medicinal chemistry research and development. It is primarily needed by R&D laboratories and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to develop new drug candidates or functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of potential therapeutic agents, especially those targeting specific enzymes or receptors.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) and develop novel bioactive compounds.
• Agrochemical Development: Acts as a building block for creating new candidates for crop protection products, such as herbicides or fungicides.
• Material Science Precursor: Utilized in the development of organic electronic materials, including OLEDs or semiconductors, due to its conjugated quinoline system.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and target identification.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	6-Bromo-2-(5-Methylthiophen-2-Yl)Quinoline-4-Carboxylic Acid
CAS No.	350998-05-9
Molecular Formula	C₁₅H₁₀BrNO₂S
Molecular Weight	348.22 g/mol
Synonyms	6-Bromo-2-(5-methyl-2-thienyl)-4-quinolinecarboxylic acid; 2-(5-Methylthiophen-2-yl)-6-bromoquinoline-4-carboxylic acid; 4-Quinolinecarboxylic acid, 6-bromo-2-(5-methyl-2-thienyl)-; 6-Bromo-2-(5-methyl-2-thienyl)quinoline-4-carboxylic acid; CAS 350998-05-9
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-(5-Methylthiophen-2-Yl)Quinoline-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.