Description

2-(5-Chloro-Thiophen-2-Yl)-Quinoline-4-Carboxylic Acid Hydrazide is a high-purity, advanced pharmaceutical intermediate with a quinoline-thiophene hybrid structure. This compound matters for its critical role as a versatile building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic frameworks. Pharmaceutical R&D teams, agrochemical innovators, and specialty chemical manufacturers need this precise intermediate to develop new drug candidates and high-value fine chemicals with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinoline-based drug candidates for oncology, anti-infective, and anti-inflammatory applications.
• Agrochemical Research: Serves as a building block for developing new generation pesticides and herbicides with specific mode-of-action targets.
• Material Science: Used in the research and development of organic electronic materials, such as OLEDs and sensors, due to its conjugated quinoline-thiophene system.
• Chemical Biology & Proteomics: Employed as a specialized reagent or linker in the design of chemical probes for studying enzyme function and protein interactions.
• Academic & Industrial R&D: A valuable compound for medicinal chemistry programs focused on structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	2-(5-Chloro-Thiophen-2-Yl)-Quinoline-4-Carboxylic Acid Hydrazide
CAS No.	350997-65-8
Molecular Formula	C14H10ClN3OS
Molecular Weight	303.76 g/mol
Synonyms	2-(5-Chloro-2-thienyl)-4-quinolinecarboxylic acid hydrazide; 2-(5-Chlorothiophen-2-yl)quinoline-4-carbohydrazide; 4-Quinolinecarboxylic acid, 2-(5-chloro-2-thienyl)-, hydrazide; 350997-65-8; Quinoline-4-carboxylic acid, 2-(5-chloro-2-thienyl)-, hydrazide; 2-(5-Chloro-thiophen-2-yl)-quinoline-4-carboxylic acid hydrazide
EINECS	Contact for details

Quality Control

Our 2-(5-Chloro-Thiophen-2-Yl)-Quinoline-4-Carboxylic Acid Hydrazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its light-sensitive nature and potential for oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.