Description

2-Bromo-3,4-Difluoronitrobenzene is a high-purity halogenated nitrobenzene derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine, fluorine, and nitro substituents, makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring difluorinated aromatic cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the bromine and fluorine atoms enhance biological activity and metabolic stability.
• Material Science Research: Employed in the creation of specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing nitro group.
• Cross-Coupling Reactions: Serves as a versatile substrate in Suzuki, Stille, and Buchwald-Hartwig amination reactions, leveraging the bromine atom for palladium-catalyzed transformations.
• Fluorine Chemistry: Acts as a starting material for further fluorination or functionalization studies, exploring the unique effects of fluorine in medicinal chemistry.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in chemical manufacturing.

Basic Information

Product Name	2-Bromo-3,4-Difluoronitrobenzene
CAS No.	350699-92-2
Molecular Formula	C6H2BrF2NO2
Molecular Weight	237.99 g/mol
Synonyms	1-Bromo-2,3-difluoro-4-nitrobenzene; 2,3-Difluoro-6-nitrobenzene bromide; Benzene, 1-bromo-2,3-difluoro-4-nitro-; 2-Bromo-3,4-difluoro-1-nitrobenzene; 3,4-Difluoro-2-bromonitrobenzene; 2,3-Difluoro-4-nitrobenzene bromide; 2-Bromo-3,4-difluoronitrobenzene (primary name)
EINECS	Contact for details

Quality Control

Our 2-Bromo-3,4-Difluoronitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the stringent requirements for research and scale-up applications in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or otherwise opaque.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.