Description

3-Quinolinecarboxylic Acid, 7-[4-[[4-(Acetylamino)Phenyl]Sulfonyl]-1-Piperazinyl]-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxo- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of novel fluoroquinolone antibiotics, offering a key building block for research and development in antimicrobial therapies. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and new drug discovery.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of next-generation fluoroquinolone antibiotic candidates.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to develop new antimicrobial agents.
• Active Pharmaceutical Ingredient (API) Development: Serves as a critical intermediate in the multi-step synthesis of complex API molecules targeting bacterial infections.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for pharmaceutical clients.
• Biochemical Research: Investigated for its mechanism of action and interaction with bacterial DNA gyrase and topoisomerase IV enzymes.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 7-[4-[[4-(Acetylamino)Phenyl]Sulfonyl]-1-Piperazinyl]-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxo-
CAS No.	350680-42-1
Molecular Formula	C25H25FN4O5S
Molecular Weight	512.56 g/mol
Synonyms	7-[4-[[4-(Acetylamino)Phenyl]Sulfonyl]-1-Piperazinyl]-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxo-3-Quinolinecarboxylic Acid; 1-Cyclopropyl-6-fluoro-7-(4-(4-(N-acetylsulfanilyl)piperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid; 1-Cyclopropyl-6-fluoro-7-[4-(4-sulfanilylpiperazin-1-yl)]-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid derivative; Garenoxacin Intermediate; T-3811 Intermediate; Fluoroquinolone Derivative; Advanced Quinolone Intermediate
EINECS	Contact for details

Quality Control

Our production of this high-purity pharmaceutical intermediate adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting specifications for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.