Description

2-Amino-4-(4-Chlorophenyl)-1-(2-Fluorophenyl)-5-Oxo-1,4,5,6,7,8-Hexahydro-3-Quinolinecarbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound matters as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), enabling research and development in targeted therapeutic areas. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and contract research organizations (CROs) focused on developing new chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Fine Chemical Synthesis: Used in multi-step organic synthesis to construct complex molecular architectures for specialized applications.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and cGMP production of investigational drugs.
• Academic Research: Utilized in university and institutional labs for methodological development and biochemical studies.

Basic Information

Product Name	2-Amino-4-(4-Chlorophenyl)-1-(2-Fluorophenyl)-5-Oxo-1,4,5,6,7,8-Hexahydro-3-Quinolinecarbonitrile
CAS No.	350511-73-8
Molecular Formula	C22H17ClFN3O
Molecular Weight	393.84 g/mol
Synonyms	2-Amino-4-(4-chlorophenyl)-1-(2-fluorophenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrile; 1,4,5,6,7,8-Hexahydro-2-amino-4-(4-chlorophenyl)-1-(2-fluorophenyl)-5-oxo-3-quinolinecarbonitrile; 350511-73-8; 2-Amino-1-(2-fluorophenyl)-4-(4-chlorophenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrile; Hexahydroquinolinecarbonitrile derivative
EINECS	Contact for details

Quality Control

Our 2-Amino-4-(4-Chlorophenyl)-1-(2-Fluorophenyl)-5-Oxo-1,4,5,6,7,8-Hexahydro-3-Quinolinecarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability and consistency for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.