Description

4-Chloro-3-Nitro-5-(Trifluoromethyl)Benzoic Acid is a high-value, multi-functional aromatic building block characterized by its unique trifluoromethyl and nitro substituents. This compound is essential for synthesizing advanced agrochemicals and pharmaceuticals, where its structure imparts desirable biological activity and metabolic stability. It is primarily sought after by research institutions and manufacturers in the fine chemical, agrochemical, and pharmaceutical intermediates sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting specific enzyme inhibitors.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides, leveraging the bioactivity of the trifluoromethyl group.
• Material Science Research: Serves as a monomer or functionalizing agent for creating specialty polymers with unique surface properties.
• Ligand and Catalyst Development: Employed in organic chemistry research to construct complex chelating ligands for metal catalysis.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing specialized colorants and imaging agents.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client R&D.

Basic Information

Product Name	4-Chloro-3-Nitro-5-(Trifluoromethyl)Benzoic Acid
CAS No.	350488-79-8
Molecular Formula	C8H3ClF3NO4
Molecular Weight	269.56 g/mol
Synonyms	4-Chloro-3-nitro-5-(trifluoromethyl)benzoic acid; Benzoic acid, 4-chloro-3-nitro-5-(trifluoromethyl)-; 3-Nitro-4-chloro-α,α,α-trifluoro-m-toluic acid; 5-(Trifluoromethyl)-4-chloro-3-nitrobenzoic acid; 4-Chloro-3-nitro-α,α,α-trifluoro-m-toluic acid; 350488-79-8; 4-Chloro-3-nitro-5-trifluoromethylbenzoic acid
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Nitro-5-(Trifluoromethyl)Benzoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each shipment, supporting compliance in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. The product is light-sensitive and should be handled accordingly.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.