Description

Ethanone, 2,2,2-Trifluoro-1-(4-Hydrazinophenyl)- (9Ci) is a specialized trifluoromethyl ketone derivative featuring a reactive phenylhydrazine moiety, making it a valuable building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of high-value, fluorinated target molecules, where the trifluoromethyl group imparts desirable properties like enhanced metabolic stability and lipophilicity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where the CF3 group enhances biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated polymers, liquid crystals, and organic semiconductors for electronic applications.
• Chemical Biology Probes: Utilized to create activity-based probes and fluorinated tags for studying enzyme mechanisms and protein labeling.
• Custom Synthesis & Contract Manufacturing: A key building block for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	Ethanone, 2,2,2-Trifluoro-1-(4-Hydrazinophenyl)- (9Ci)
CAS No.	350040-14-1
Molecular Formula	C8H7F3N2O
Molecular Weight	204.15 g/mol
Synonyms	1-(4-Hydrazinophenyl)-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-(4-hydrazinophenyl)ethanone; 4-Hydrazinophenyl trifluoromethyl ketone; p-Hydrazino-α,α,α-trifluoroacetophenone; Trifluoroacetophenone-4-hydrazone precursor; α,α,α-Trifluoro-4'-hydrazinoacetophenone; 350040-14-1; TFHA-Hz
EINECS	Contact for details

Quality Control

Our Ethanone, 2,2,2-Trifluoro-1-(4-Hydrazinophenyl)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports your cGMP and ISO-compliant workflows, ensuring reliable integration into your critical synthesis processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its easily oxidized nature, for long-term storage, consider keeping the container under an inert atmosphere (e.g., nitrogen or argon). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.