Description

6-Azabicyclo[3.1.0]Hex-2-Ene,6-Ethyl-4-Methoxy-1-Methyl-4-(1-Methylethoxy)-,(1R,4S,5R)-Rel-(9Ci) is a high-purity, stereochemically defined bicyclic amine derivative, serving as a critical advanced pharmaceutical intermediate (API intermediate). Its complex, rigid molecular architecture makes it an invaluable building block for synthesizing novel, bioactive compounds. This product is essential for research and development chemists and process scale-up teams in the pharmaceutical and agrochemical sectors, where precise stereochemistry and high purity are non-negotiable for efficacy and regulatory approval.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Research: Used as a precursor for developing novel pesticides and herbicides with specific modes of action.
• Asymmetric Catalysis Ligand Precursor: Its structure can be modified to create novel chiral ligands for asymmetric synthesis.
• Chemical Biology Probe Development: Employed in medicinal chemistry to create tool compounds for target validation and pathway analysis.
• Process Chemistry & Scale-Up: Serves as a benchmark material for developing and optimizing robust, scalable synthetic routes in pilot plants.
• Academic & Institutional Research: Used in universities and R&D institutes for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	6-Azabicyclo[3.1.0]Hex-2-Ene,6-Ethyl-4-Methoxy-1-Methyl-4-(1-Methylethoxy)-,(1R,4S,5R)-Rel-(9Ci)
CAS No.	349611-74-1
Molecular Formula	C12H21NO2
Molecular Weight	211.30 g/mol
Synonyms	(1R,4S,5R)-rel-6-Ethyl-4-methoxy-1-methyl-4-(1-methylethoxy)-6-azabicyclo[3.1.0]hex-2-ene; 6-Azabicyclo[3.1.0]hex-2-ene, 6-ethyl-4-methoxy-1-methyl-4-(1-methylethoxy)-, (1R,4S,5R)-rel-; 349611-74-1; Bicyclic amine ether derivative; (1R,4S,5R)-rel-6-Ethyl-4-isopropoxy-4-methoxy-1-methyl-6-azabicyclo[3.1.0]hex-2-ene
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced under strict quality management systems. We employ state-of-the-art analytical techniques, including HPLC, GC, NMR, and chiral analysis, to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment. Our quality commitment aligns with cGMP principles for pharmaceutical applications, ensuring traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.