Description

n-(2-Nitrobenzenesulfonyl)-1,4-Diaminobutane Hydrochloride is a specialized organic intermediate featuring a nitrobenzenesulfonyl protecting group and a diamine backbone. This compound is valued for its role in sophisticated multi-step organic synthesis, particularly in the preparation of complex molecules and active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing novel compounds and advanced materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs), particularly those requiring protected amine functionalities.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis as a reagent for introducing specific side chains or as a protected diamine linker.
• Agrochemical Synthesis: Serves as an intermediate in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Dye and Pigment Manufacturing: Employed in the synthesis of specialized azo dyes and high-performance pigments where the nitro and sulfonyl groups contribute to color and stability properties.
• Polymer Modification: Acts as a monomer or cross-linking agent in the production of specialty polyamides, polyurethanes, and epoxy resins with enhanced properties.
• Bioconjugation and Probe Development: Utilized in biochemical research for labeling proteins, antibodies, or other biomolecules due to its reactive amine groups and the photolabile or reducible nitro group.
• Academic and Industrial R&D: A valuable reagent for methodological development in organic chemistry and for exploring new chemical entities in various high-tech sectors.

Basic Information

Product Name	n-(2-Nitrobenzenesulfonyl)-1,4-Diaminobutane Hydrochloride
CAS No.	349553-74-8
Molecular Formula	C10H16ClN3O4S
Molecular Weight	309.77 g/mol
Synonyms	1,4-Butanediamine, N1-(2-nitrobenzenesulfonyl)-, hydrochloride; N1-(2-Nitrobenzenesulfonyl)butane-1,4-diamine hydrochloride; 4-[(2-Nitrobenzenesulfonyl)amino]butylamine hydrochloride; 2-Nitro-N-(4-aminobutyl)benzenesulfonamide hydrochloride; o-Nitrobenzenesulfonyl-1,4-diaminobutane HCl; Nosyl-protected butanediamine hydrochloride; 349553-74-8
EINECS	Contact for details

Quality Control

Our n-(2-Nitrobenzenesulfonyl)-1,4-Diaminobutane Hydrochloride is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets high-purity standards suitable for research and synthesis. Certificates of Analysis (COA) documenting all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The product is light-sensitive (store away from light). Keep container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.