Description

Boc-Hse(Me)-Oh Dcha is a protected amino acid derivative, specifically the dicyclohexylamine (DCHA) salt of Boc-L-homoserine(Me)-OH. This compound is a crucial chiral building block in the synthesis of complex peptides and peptidomimetics, offering enhanced solubility and handling properties for advanced pharmaceutical research. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the solid-phase and solution-phase synthesis of peptide-based drugs and bioactive compounds.
• Peptidomimetic Research: Used to incorporate modified homoserine residues into peptide chains to study structure-activity relationships (SAR) and improve metabolic stability.
• API Development: Serves as a critical starting material or intermediate in the development and scale-up of Active Pharmaceutical Ingredients (APIs).
• Bioconjugation: Useful in the preparation of peptide conjugates for drug delivery systems, diagnostics, and biophysical studies.
• Chemical Biology Probes: Employed in the synthesis of labeled or tagged peptides used as tools for probing biological mechanisms and protein interactions.

Basic Information

Product Name	Boc-Hse(Me)-Oh Dcha
CAS No.	349545-91-1
Molecular Formula	C₂₂H₄₂N₂O₅
Molecular Weight	414.59 g/mol
Synonyms	Boc-L-homoserine(Me)-OH dicyclohexylamine salt; (2S)-2-[(tert-Butoxycarbonyl)amino]-4-methoxybutanoic acid compound with dicyclohexylamine; N-(tert-Butoxycarbonyl)-O-methyl-L-homoserine DCHA salt; Boc-O-methyl-L-homoserine DCHA salt; Boc-Homoserine(Me)-OH·DCHA; Boc-L-Hse(OMe)-OH DCHA salt; Boc-4-methoxy-L-homoalanine DCHA salt
EINECS	Contact for details

Quality Control

Our Boc-Hse(Me)-Oh Dcha is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A Certificate of Analysis (COA) detailing specific results for identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.