Description

1-(1-Methylpiperidin-4-Yl)Piperazine 3Hcl is a high-purity, trihydrochloride salt derivative of a substituted piperazine-piperidine compound, serving as a critical building block in advanced organic synthesis. This compound is valued for its role as a versatile intermediate in the development of complex, biologically active molecules. It is primarily sought by research institutions and pharmaceutical companies engaged in medicinal chemistry, drug discovery, and process development.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and receptor-targeted drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for constructing libraries of compounds for high-throughput screening and structure-activity relationship (SAR) studies.
• Chemical Synthesis: Employed in multi-step organic synthesis to introduce the 1-(1-methylpiperidin-4-yl)piperazine moiety into more complex molecular architectures.
• Active Pharmaceutical Ingredient (API) Development: Serves as a starting material or intermediate in the synthesis pathway of potential APIs requiring this specific nitrogen-containing heterocyclic system.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services for the life sciences industry.

Basic Information

Item	Details
Product Name	1-(1-Methylpiperidin-4-Yl)Piperazine 3Hcl
CAS No.	349535-15-5
Molecular Formula	C10H22Cl3N3
Molecular Weight	290.66 g/mol
Synonyms	1-(1-Methyl-4-piperidyl)piperazine trihydrochloride; 1-(1-Methylpiperidin-4-yl)piperazine hydrochloride (1:3); 1-(1-Methyl-4-piperidinyl)piperazine trihydrochloride; 4-(1-Methylpiperidin-4-yl)piperazine trihydrochloride; 1-Methyl-4-(piperazin-1-yl)piperidine trihydrochloride; N-Methyl-4-piperidylpiperazine trihydrochloride; CAS 349535-15-5
EINECS	Contact for details

Quality Control

Every batch of 1-(1-Methylpiperidin-4-Yl)Piperazine 3Hcl is manufactured and tested under strict quality management protocols. We ensure compliance with high-purity standards suitable for research and development applications. Comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, is performed to verify identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment to prevent absorption of atmospheric moisture, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.