Description

Hydrazinecarboxylic Acid, 2-[(Tetrahydro-2-Furanyl)Methyl]-, 1,1-Dimethylethyl Ester is a specialized, high-purity chemical intermediate of significant interest in advanced organic synthesis. Its value lies in its unique molecular architecture, which incorporates both a protected hydrazinecarboxylate and a tetrahydrofuran moiety, making it a versatile building block for constructing complex heterocyclic frameworks. This compound is primarily needed by research and development chemists and process scale-up teams within the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the tetrahydrofuran scaffold's bioisosteric properties.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the hydrazine derivative can impart specific biological activity.
• Ligand and Catalyst Development: Acts as a starting material for creating novel chiral ligands or organocatalysts used in asymmetric synthesis.
• Heterocyclic Chemistry: A crucial building block for the construction of complex nitrogen- and oxygen-containing heterocycles, such as fused pyrazoles and morpholines.
• Peptidomimetic Research: Employed in the design and synthesis of peptidomimetics, where it can mimic peptide bonds or introduce conformational constraints.
• Material Science Research: Investigated as a monomer or cross-linking agent for developing novel polymers with specific thermal or mechanical properties.

Basic Information

Product Name	Hydrazinecarboxylic Acid, 2-[(Tetrahydro-2-Furanyl)Methyl]-, 1,1-Dimethylethyl Ester
CAS No.	349111-21-3
Molecular Formula	C11H20N2O3
Molecular Weight	228.29 g/mol
Synonyms	tert-Butyl 2-[(tetrahydrofuran-2-yl)methyl]hydrazine-1-carboxylate; 1,1-Dimethylethyl 2-[(Tetrahydro-2-furanyl)methyl]hydrazinecarboxylate; N-Boc-N'-(tetrahydrofurfuryl)hydrazine; Boc-NH-NH-CH2-THF; (Tetrahydrofuran-2-ylmethyl)hydrazine, N-Boc protected; BOC-Hydrazine-THF derivative; 2-[(Oxolan-2-yl)methyl]hydrazine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our production of Hydrazinecarboxylic Acid, 2-[(Tetrahydro-2-Furanyl)Methyl]-, 1,1-Dimethylethyl Ester (CAS 349111-21-3) adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and GC for residual solvent analysis, to ensure consistency and reliability for your critical synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, and we support compliance with cGMP, REACH, and other relevant regulatory frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.