Description

8-Bromo-1,2,3,4-Tetrahydronaphthalen-1-Amine is a versatile brominated tetralin amine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique structure, which provides a reactive amine group and a bromine substituent on a partially saturated naphthalene scaffold, enabling diverse functionalization pathways. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of complex molecules, including potential active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive scaffold.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions to construct more complex heterocyclic and polycyclic compounds.
• Material Science Research: Investigated as a monomer or functional additive in the development of specialty polymers and advanced organic materials.
• Chemical Biology Probe Development: Serves as a starting point for creating molecular probes to study biological pathways and enzyme functions.

Basic Information

Product Name	8-Bromo-1,2,3,4-Tetrahydronaphthalen-1-Amine
CAS No.	348627-52-1
Molecular Formula	C10H12BrN
Molecular Weight	226.11 g/mol
Synonyms	8-Bromo-1,2,3,4-tetrahydro-1-naphthalenamine; 1-Amino-8-bromo-1,2,3,4-tetrahydronaphthalene; 8-Bromo-1-amino-1,2,3,4-tetrahydronaphthalene; 8-Bromo-1-tetralinamine; 1,2,3,4-Tetrahydro-8-bromo-1-naphthylamine; 8-Bromo-1,2,3,4-tetrahydro-naphthalen-1-ylamine
EINECS	Contact for details

Quality Control

Our 8-Bromo-1,2,3,4-Tetrahydronaphthalen-1-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.