Description

8-Bromo-2-(Piperazin-1-Yl)Quinoline is a high-value, heterocyclic organic compound featuring a quinoline core substituted with a bromine atom and a piperazine moiety, making it a versatile and crucial building block in advanced chemical synthesis. This compound is specifically engineered to serve as a key intermediate in the development of complex molecules, offering precise structural control for researchers and manufacturers. It is primarily sought after by the pharmaceutical, agrochemical, and advanced materials sectors for applications in drug discovery, ligand synthesis, and the creation of functional organic materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the quinoline-piperazine structure can contribute to novel modes of action.
• Ligand Synthesis: Acts as a key scaffold for creating specialized ligands in catalysis and metal-organic frameworks (MOFs) for separation and sensing applications.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Material Science: Employed in the research of organic semiconductors, light-emitting diodes (OLEDs), and other electronic materials due to its conjugated quinoline system.
• Academic & Contract Research: A fundamental reagent for synthetic organic chemistry research in academic institutions and contract research organizations (CROs).

Basic Information

Product Name	8-Bromo-2-(Piperazin-1-Yl)Quinoline
CAS No.	348133-70-0
Molecular Formula	C₁₃H₁₅BrN₃
Molecular Weight	293.18 g/mol
Synonyms	8-Bromo-2-(1-piperazinyl)quinoline; 2-(Piperazin-1-yl)-8-bromoquinoline; Quinoline, 8-bromo-2-(1-piperazinyl)-; 8-Bromo-2-piperazin-1-ylquinoline; 348133-70-0; 8-Br-2-Piperazinylquinoline
EINECS	Contact for details

Quality Control

Our 8-Bromo-2-(Piperazin-1-Yl)Quinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.