Description

8-Boc-3,8-Diaza-Bicyclo[3.2.1]Octane, Hcl is a high-purity, protected bicyclic amine derivative, widely recognized as a crucial building block in advanced organic synthesis. Its value lies in its role as a versatile scaffold for constructing complex nitrogen-containing molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working in drug discovery, agrochemicals, and specialty chemical manufacturing.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and antiviral drug candidates.
• Medicinal Chemistry Scaffold: Used to introduce the constrained 3,8-diazabicyclo[3.2.1]octane pharmacophore, which can modulate bioavailability and receptor binding affinity.
• Ligand Synthesis: Employed in the development of novel catalysts and chelating agents for asymmetric synthesis and metal complexation.
• Agrochemical Research: Serves as a building block for novel herbicides, fungicides, and insecticides that require specific nitrogen-containing heterocycles.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	8-Boc-3,8-Diaza-Bicyclo[3.2.1]Octane, Hcl
CAS No.	347195-73-7
Molecular Formula	C11H21N3O2 • HCl
Molecular Weight	263.77 g/mol (Free base: 227.30 g/mol)
Synonyms	3,8-Diazabicyclo[3.2.1]octane-8-carboxylic acid, 1,1-dimethylethyl ester, hydrochloride; tert-Butyl 3,8-diazabicyclo[3.2.1]octane-8-carboxylate hydrochloride; 8-(tert-Butoxycarbonyl)-3,8-diazabicyclo[3.2.1]octane hydrochloride; 8-Boc-3,8-diazabicyclo[3.2.1]octane HCl; BOC-DABO HCl; 347195-73-7; 8-N-Boc-3,8-diazabicyclo[3.2.1]octane hydrochloride
EINECS	Contact for details

Quality Control

Our 8-Boc-3,8-Diaza-Bicyclo[3.2.1]Octane, Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with full traceability are provided for every shipment, confirming compliance with customer specifications and industry best practices for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.