Description

8-(Trifluoromethyl)Quinolin-3-Amine is a high-purity, functionalized quinoline derivative characterized by its trifluoromethyl and amine substituents. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in modern synthetic chemistry. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology, antiviral, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides, leveraging the biological activity of the quinoline scaffold.
• Organic Light-Emitting Diodes (OLEDs): Acts as an electron-transporting or host material precursor in the manufacture of advanced display and lighting technologies.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and asymmetric synthesis.
• Fluorescent Probe and Dye Chemistry: Utilized in the synthesis of fluorophores and molecular probes for bio-imaging and diagnostic applications.
• Material Science Research: Employed as a monomer or functional additive in the development of polymers and advanced organic materials.

Basic Information

Product Name	8-(Trifluoromethyl)Quinolin-3-Amine
CAS No.	347146-22-9
Molecular Formula	C10H7F3N2
Molecular Weight	212.17 g/mol
Synonyms	3-Amino-8-(trifluoromethyl)quinoline; 8-(Trifluoromethyl)-3-quinolinamine; 8-Trifluoromethylquinolin-3-ylamine; Quinolin-3-amine, 8-(trifluoromethyl)-; 8-CF3-Quinolin-3-amine
EINECS	Contact for details

Quality Control

Our 8-(Trifluoromethyl)Quinolin-3-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and batch-to-batch consistency for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.