Description

(2R)-N1,N1-Dimethyl-1,2-Propanediamine is a chiral diamine building block of significant interest in advanced organic synthesis. Its value lies in its stereochemical purity, which is critical for creating enantiomerically defined compounds with specific biological or material properties. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing chiral active ingredients and ligands.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Catalyst Ligand: Used in the preparation of chiral ligands for transition metal catalysis, enabling highly enantioselective reactions like hydrogenation and C-C bond formation.
• Agrochemical Synthesis: Intermediate for the production of chiral herbicides, fungicides, and plant growth regulators where specific stereochemistry impacts efficacy and environmental safety.
• Chiral Resin & Polymer Precursor: Serves as a monomer or cross-linking agent for creating specialty polymers with chiral recognition properties, used in chromatography and sensor technologies.
• Complexing Agent: Utilized in the formulation of metal-chelating agents for analytical chemistry, catalysis, and metal extraction processes.
• Research & Development: A valuable reagent for academic and industrial R&D in medicinal chemistry and synthetic methodology development.

Basic Information

Product Name	(2R)-N1,N1-Dimethyl-1,2-Propanediamine
CAS No.	346690-99-1
Molecular Formula	C5H14N2
Molecular Weight	102.18 g/mol
Synonyms	(R)-N,N-Dimethyl-1,2-diaminopropane; (R)-1-Amino-2-(dimethylamino)propane; (2R)-1,2-Propanediamine, N1,N1-dimethyl-; (R)-N,N-Dimethylpropane-1,2-diamine; (R)-DMAPDA; (R)-1,2-Diaminopropane, N,N-dimethyl-; (R)-2-(Dimethylamino)propylamine
EINECS	Contact for details

Quality Control

Our (2R)-N1,N1-Dimethyl-1,2-Propanediamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC or GC, to ensure it meets exacting standards for research and commercial use. Certificates of Analysis (COA) with detailed specifications for identity, assay, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, containers should be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC/GC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.