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Diacetato[(R)-(+)-2,2'-Bis(Diphenylphosphino)-1,1'-Binaphthyl]Ruthenium(Ii) CAS NO 346457-41-8


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CAS No.:346457-41-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Diacetato[(R)-(+)-2,2'-Bis(Diphenylphosphino)-1,1'-Binaphthyl]Ruthenium(II) is a high-value, chiral ruthenium complex widely recognized for its exceptional catalytic performance in asymmetric synthesis. This compound is crucial for achieving high enantioselectivity and yield in critical bond-forming reactions, directly impacting the efficiency and cost of producing advanced pharmaceutical intermediates and fine chemicals. It is an essential catalyst for research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to develop optically pure compounds.

Application

  • Asymmetric Hydrogenation: A premier catalyst for the enantioselective reduction of functionalized olefins, ketones, and imines to produce chiral alcohols and amines.
  • Pharmaceutical Intermediate Synthesis: Key for constructing stereogenic centers in the production of active pharmaceutical ingredients (APIs) for cardiovascular, CNS, and antiviral drugs.
  • Agrochemical Manufacturing: Used in the synthesis of chiral herbicides, fungicides, and plant growth regulators requiring specific biological activity.
  • Fine Chemical Production: Enables the commercial-scale synthesis of complex, high-value fragrance and flavor compounds.
  • Academic & Process R&D: A benchmark catalyst for developing new asymmetric methodologies and optimizing catalytic processes in laboratory settings.
  • Transfer Hydrogenation: Effective in asymmetric transfer hydrogenation reactions using isopropanol or formic acid as the hydrogen source.

Basic Information

Product Name Diacetato[(R)-(+)-2,2'-Bis(Diphenylphosphino)-1,1'-Binaphthyl]Ruthenium(II)
CAS No. 346457-41-8
Molecular Formula C56H44O4P2Ru
Molecular Weight 934.96 g/mol
Synonyms (R)-RuBINAP Diacetate; (R)-BINAP-Ru(OAc)2; Ruthenium(II) (R)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl diacetate; (R)-Ru(OAc)2(binap); [Ru((R)-binap)(OAc)2]; (R)-BINAP-Ruthenium Diacetate Complex; Ru((R)-BINAP)(OAc)2; (R)-BINAP-Ru(II) diacetate
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Quality Control

Our Diacetato[(R)-(+)-2,2'-Bis(Diphenylphosphino)-1,1'-Binaphthyl]Ruthenium(II) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high catalytic activity. Each lot undergoes comprehensive analysis, including chiral purity and metal content assays. A Certificate of Analysis (COA) detailing specifications such as purity, solvent residues, and performance in model reactions is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to maintain stability and prevent oxidation. The container should be kept in a cool, dry, and well-ventilated area separate from incompatible materials.

Specification

Item Specification
Appearance Reddish-brown to brown crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Chiral Purity (HPLC) ≥ 99.0% ee
Ruthenium Content 10.5 - 11.5 %
Solvent Residues (GC) Meet ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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