Description

2-Bromo-4-Fluoro-5-Nitroaniline is a halogenated nitroaniline derivative that serves as a versatile and high-value synthetic intermediate. Its molecular structure, featuring bromine, fluorine, and nitro substituents on an aniline core, makes it a critical building block for constructing complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries. It is used to introduce specific functional groups and modulate the biological activity of target compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the halogen and nitro groups contribute to bioactivity.
• Material Science Research: Serves as a precursor for functional dyes, pigments, and advanced organic electronic materials due to its electron-withdrawing substituents.
• Chemical Research & Development: Employed in organic synthesis for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a substrate for further functionalization.
• Ligand and Catalyst Preparation: Useful for synthesizing specialized ligands used in catalysis and molecular recognition studies.

Basic Information

Product Name	2-Bromo-4-Fluoro-5-Nitroaniline
CAS No.	346433-97-4
Molecular Formula	C6H4BrFN2O2
Molecular Weight	235.01 g/mol
Synonyms	5-Amino-2-bromo-4-fluoronitrobenzene; 2-Bromo-4-fluoro-5-nitrobenzenamine; 1-Amino-2-bromo-4-fluoro-5-nitrobenzene; Benzenamine, 2-bromo-4-fluoro-5-nitro-; 346433-97-4; 2-Bromo-4-fluoro-5-nitro-phenylamine; 5-Nitro-2-bromo-4-fluoroaniline
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Fluoro-5-Nitroaniline is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as identity (IR, NMR), purity (HPLC), and impurity profiles. Our quality system is designed to support cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.