Description

Di-Fmoc-3,4-Diaminobenzoic Acid is a high-purity, bifunctional protected amino acid derivative essential for advanced organic synthesis. This compound serves as a critical building block for the solid-phase and solution-phase synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the fields of peptide chemistry, medicinal chemistry, and materials science for constructing novel compounds and active pharmaceutical ingredients (APIs).

Application

• Peptide Synthesis: A key protected intermediate for the incorporation of 3,4-diaminobenzoic acid into peptide backbones, enabling the creation of novel peptide architectures.
• Pharmaceutical Intermediates: Serves as a crucial precursor in the research and development of new drug candidates, especially those targeting specific protein interactions.
• Combinatorial Chemistry: Used in the generation of diverse chemical libraries for high-throughput screening in drug discovery programs.
• Bioconjugation: Facilitates the site-specific labeling and modification of biomolecules due to its orthogonal protecting groups and reactive carboxylic acid functionality.
• Materials Science: Acts as a monomer or cross-linker in the synthesis of specialized polymers and dendrimers with tailored properties.
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying biological processes and enzyme mechanisms.

Basic Information

Product Name	Di-Fmoc-3,4-Diaminobenzoic Acid
CAS No.	345958-22-7
Molecular Formula	C39H30N2O6
Molecular Weight	622.67 g/mol
Synonyms	3,4-Bis[(9H-fluoren-9-ylmethoxy)carbonylamino]benzoic Acid; N3,N4-Bis(9-fluorenylmethoxycarbonyl)-3,4-diaminobenzoic Acid; 3,4-Diaminobenzoic Acid Di-Fmoc Derivative; Fmoc-Dab(3,4-OH)-OH (protected form); Di-Fmoc-DABA; 3,4-Di-Fmoc-aminobenzoic Acid; 3,4-Bis(Fmoc-amino)benzoic Acid
EINECS	Contact for details

Quality Control

Our Di-Fmoc-3,4-Diaminobenzoic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.