Description

Spiro[Cyclopropane-1,8(5H)-Imidazo[1,5-A]Pyridine] (9Ci) CAS NO 345633-67-2 is a sophisticated spirocyclic organic compound featuring a fused imidazopyridine core, representing a valuable and versatile chemical building block. Its unique three-dimensional structure and nitrogen-rich heterocyclic system make it a critical intermediate for advanced research and development in medicinal chemistry. This compound is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for the synthesis of novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used as a privileged scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Employed in the research and synthesis of new-generation pesticides and herbicides, leveraging its complex heterocyclic structure.
• Material Science: Investigated as a building block for advanced organic electronic materials and ligands in catalytic systems.
• Academic & Contract Research: Supplied to universities and CROs (Contract Research Organizations) for fundamental organic synthesis and methodological studies.

Basic Information

Product Name	Spiro[Cyclopropane-1,8(5H)-Imidazo[1,5-A]Pyridine] (9Ci)
CAS No.	345633-67-2
Molecular Formula	C9H10N2
Molecular Weight	146.19 g/mol
Synonyms	Spiro[cyclopropane-1,8(5H)-imidazo[1,5-a]pyridine]; 8-Azaspiro[4.5]deca-1,3,6,9-tetraene; 1H-Imidazo[1,5-a]pyridine, 2,3-dihydrospiro[cyclopropane-1,8]-; Spiro(cyclopropane-1,8(5H)-imidazo[1,5-a]pyridine); 345633-67-2; Spirocyclic imidazopyridine; 8-Azaspiro[4.5]deca-1,3,6,9-tetraen-7-amine (related derivative)
EINECS	Contact for details

Quality Control

Our Spiro[Cyclopropane-1,8(5H)-Imidazo[1,5-A]Pyridine] (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.