Description

Hydrazinecarboxylic Acid, 2-(Trimethylsilyl)-, 1,1-Dimethylethyl Ester (9Ci) is a specialized organosilicon-protected hydrazine derivative, serving as a versatile building block in advanced organic synthesis. Its primary value lies in its role as a protected hydrazine reagent, enabling controlled reactions in sensitive synthetic pathways where the free hydrazine group would be incompatible. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for constructing heterocyclic compounds and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of nitrogen-containing heterocycles, such as pyrazoles and triazoles, found in various drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides that require specific hydrazine-based functional groups.
• Peptide Chemistry: Acts as a protected reagent in the synthesis of modified peptides and peptide mimetics.
• Material Science Research: Employed in the development of novel polymers and functional materials with tailored properties.
• Cross-Coupling Reactions: Serves as a precursor for generating reactive intermediates in palladium-catalyzed and other metal-mediated couplings.
• Academic & R&D Laboratories: A valuable reagent for methodological development and exploring new synthetic routes in organic chemistry.

Basic Information

Product Name	Hydrazinecarboxylic Acid, 2-(Trimethylsilyl)-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	345581-39-7
Molecular Formula	C9H22N2O2Si
Molecular Weight	218.37 g/mol
Synonyms	tert-Butyl 2-(trimethylsilyl)hydrazine-1-carboxylate; 1,1-Dimethylethyl 2-(Trimethylsilyl)hydrazinecarboxylate; Boc-NNH-TMS; N-(tert-Butoxycarbonyl)-N'-(trimethylsilyl)hydrazine; tert-Butyl N'-(trimethylsilyl)hydrazinecarboxylate; 2-(Trimethylsilyl)hydrazinecarboxylic Acid tert-Butyl Ester; TMS-Protected Boc-Hydrazine; (Trimethylsilyl)hydrazine, N-Boc protected
EINECS	Contact for details

Quality Control

Our Hydrazinecarboxylic Acid, 2-(Trimethylsilyl)-, 1,1-Dimethylethyl Ester (9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC for assay and purity, NMR for structural confirmation, and Karl Fischer titration for moisture content. Comprehensive Certificates of Analysis (COA) documenting all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.