Description

1-(3-Nitrophenyl)-5-Oxo-3-Pyrrolidinecarboxylic Acid is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 345297-65-6. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic agents and high-value products.

Application

This versatile intermediate serves key functions in research and industrial synthesis. Its primary applications include:

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its nitrophenyl and pyrrolidinone motifs.
• Chemical Research & Development: Serves as a valuable scaffold for medicinal chemistry, enabling the exploration of new chemical entities and structure-activity relationships (SAR).
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and other performance materials requiring complex heterocyclic structures.

Basic Information

Product Name	1-(3-Nitrophenyl)-5-Oxo-3-Pyrrolidinecarboxylic Acid
CAS No.	345297-65-6
Molecular Formula	C11H10N2O5
Molecular Weight	250.21 g/mol
Synonyms	3-Pyrrolidinecarboxylic acid, 1-(3-nitrophenyl)-5-oxo-; 1-(3-Nitrophenyl)-5-oxopyrrolidine-3-carboxylic acid; 5-Oxo-1-(3-nitrophenyl)pyrrolidine-3-carboxylic acid; 345297-65-6; 1-(3-Nitrophenyl)-5-pyrrolidinone-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 1-(3-Nitrophenyl)-5-Oxo-3-Pyrrolidinecarboxylic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy. Our products are manufactured in facilities that follow cGMP (current Good Manufacturing Practice) guidelines where applicable. A detailed Certificate of Analysis (COA) is provided with every shipment to ensure full traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.