Description

1H-Indene-1,5-Diol, Octahydro-1,4,4,7A-Tetramethyl-, (1R,3Ar,5S,7As)-Rel- (9Ci) is a high-purity, stereochemically defined diol derivative of indane, serving as a critical chiral building block and advanced pharmaceutical intermediate. Its precise stereochemistry and functional groups make it invaluable for synthesizing complex molecules with specific biological activity. This compound is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder drug candidates.
• Asymmetric Synthesis: Utilized as a sophisticated starting material or ligand precursor in catalytic asymmetric reactions to induce high enantioselectivity.
• Fine Chemical Production: Serves as a building block for the synthesis of specialty chemicals, fragrances, and advanced materials requiring specific stereochemical configurations.
• Academic & Industrial Research: Employed in methodological studies and process chemistry research to explore new synthetic pathways and reaction mechanisms.
• Agrochemical Intermediate: Potential use in the synthesis of chiral, bioactive compounds for crop protection and agrochemical applications.

Basic Information

Product Name	1H-Indene-1,5-Diol, Octahydro-1,4,4,7A-Tetramethyl-, (1R,3Ar,5S,7As)-Rel- (9Ci)
CAS No.	344942-26-3
Molecular Formula	C13H24O2
Molecular Weight	212.33 g/mol
Synonyms	rel-(1R,3aR,5S,7aS)-Octahydro-1,4,4,7a-tetramethyl-1H-indene-1,5-diol; (1R,3aR,5S,7aS)-1,5-Dihydroxy-1,4,4,7a-tetramethyloctahydro-1H-indene; Octahydro-1,4,4,7a-tetramethyl-1H-indene-1,5-diol, (1R,3aR,5S,7aS)-rel-; 1H-Indene-1,5-diol, octahydro-1,4,4,7a-tetramethyl-, (1R,3aR,5S,7aS)-rel-; Chiral Indane Diol Derivative; Tetramethylindanediol
EINECS	Contact for details

Quality Control

Every batch of 1H-Indene-1,5-Diol, Octahydro-1,4,4,7A-Tetramethyl-, (1R,3Ar,5S,7As)-Rel- (9Ci) is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity consistent with research and development standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.