Description

(S)-1-(p-Tolyl)Butan-1-Amine Hydrochloride is a high-purity chiral amine salt, a critical building block in advanced organic synthesis. Its value lies in its role as a key intermediate for the development of enantiomerically pure pharmaceuticals and agrochemicals, where stereochemical integrity is paramount. This compound is essential for research chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries seeking to create novel active ingredients with high specificity.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the research and development of chiral herbicides, fungicides, and pesticides, where the (S)-enantiomer often provides the desired biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to induce stereoselectivity in chemical reactions.
• Fine Chemical Manufacturing: Employed in the production of specialty chemicals, flavors, and fragrances that require specific stereochemistry.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and for exploring new synthetic pathways in medicinal chemistry.

Basic Information

Product Name	(S)-1-(p-Tolyl)Butan-1-Amine Hydrochloride
CAS No.	344794-57-6
Molecular Formula	C11H17N·HCl
Molecular Weight	199.72 g/mol
Synonyms	(S)-1-(4-Methylphenyl)butan-1-amine hydrochloride; (S)-1-(p-Tolyl)butylamine hydrochloride; (S)-4-Methyl-α-propylbenzenemethanamine hydrochloride; (S)-α-Propyl-p-toluidine hydrochloride; (S)-1-(4-Methylphenyl)-1-butanamine hydrochloride; (S)-1-(p-Tolyl)butanamine HCl; (S)-1-(4-Tolyl)butan-1-amine hydrochloride
EINECS	Contact for details

Quality Control

Every batch of (S)-1-(p-Tolyl)Butan-1-Amine Hydrochloride is manufactured under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards for chiral purity and chemical identity. Certificates of Analysis (COA) detailing chiral HPLC assay, enantiomeric excess (ee), and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.