Description

cis-5,6,7,8-Tetrahydro-6,7-dihydroxy-1-naphthol is a specialized dihydroxylated tetralin derivative, a key chiral intermediate in fine chemical synthesis. Its precise stereochemistry and functional group arrangement make it a valuable building block for creating complex molecules with high optical purity. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical and advanced materials sectors. Its controlled synthesis and consistent quality are critical for downstream process reliability and final product efficacy.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Asymmetric Catalyst Ligand Precursor: Used in the development of novel chiral ligands for asymmetric catalysis, enabling enantioselective transformations.
• Advanced Material Monomer: Acts as a functional monomer for synthesizing specialty polymers and liquid crystals with specific optical or electronic properties.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex polycyclic and heterocyclic compound libraries.
• Analytical Reference Standard: Provides a high-purity standard for method development and quality control in analytical laboratories.

Basic Information

Product Name	cis-5,6,7,8-Tetrahydro-6,7-dihydroxy-1-naphthol
CAS No.	344764-57-4
Molecular Formula	C₁₀H₁₂O₃
Molecular Weight	180.20 g/mol
Synonyms	cis-5,6,7,8-Tetrahydro-6,7-dihydroxynaphthalen-1-ol; (6R,7S)-5,6,7,8-Tetrahydro-6,7-dihydroxy-1-naphthol; 1-Naphthol, 5,6,7,8-tetrahydro-6,7-dihydroxy-, cis-; Tetrahydrodihydroxynaphthol; Chiral tetralin diol
EINECS	Contact for details

Quality Control

Our cis-5,6,7,8-Tetrahydro-6,7-dihydroxy-1-naphthol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformity to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.