Description

2-Cyclopentene-1-Methanol,5-Ethoxy-,Methanesulfonate,(1R,5R)-Rel-(9Ci) CAS NO 344327-57-7 is a high-purity, chiral cyclopentene derivative functionalized with ethoxy and methanesulfonate groups. This compound serves as a critical chiral building block and advanced pharmaceutical intermediate, enabling the synthesis of complex, stereochemically defined molecules. It is essential for research and development in the pharmaceutical, agrochemical, and fine chemical sectors, where precise stereochemistry is paramount for biological activity and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anti-inflammatory, or central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of chiral pesticides and herbicides, where specific stereoisomers often exhibit enhanced efficacy and lower environmental impact.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing novel chiral ligands or organocatalysts used in stereoselective transformations.
• Fine Chemical & Specialty Chemical Production: Employed in the manufacture of complex fragrance ingredients, flavors, and other high-value specialty chemicals requiring defined stereochemistry.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis, including studies on ring-opening reactions, nucleophilic substitutions, and stereocontrol.
• Process Chemistry & Scale-Up: Used in route scouting and optimization for the commercial-scale production of stereochemically complex molecules.

Basic Information

Product Name	2-Cyclopentene-1-Methanol,5-Ethoxy-,Methanesulfonate,(1R,5R)-Rel-(9Ci)
CAS No.	344327-57-7
Molecular Formula	C9H16O4S
Molecular Weight	220.29 g/mol
Synonyms	(1R,5R)-rel-5-Ethoxy-2-cyclopenten-1-ylmethyl methanesulfonate; (1R,5R)-rel-5-Ethoxy-2-cyclopentene-1-methanol methanesulfonate; (1R,5R)-rel-5-Ethoxy-2-cyclopenten-1-ylmethyl mesylate; 5-Ethoxy-2-cyclopenten-1-ylmethyl methanesulfonate, (1R,5R)-rel-; Methanesulfonic acid, [(1R,5R)-rel-5-ethoxy-2-cyclopenten-1-yl]methyl ester; 344327-57-7; (rel)-(1R,5R)-5-Ethoxy-2-cyclopenten-1-ylmethyl methanesulfonate
EINECS	Contact for details

Quality Control

Our production of 2-Cyclopentene-1-Methanol,5-Ethoxy-,Methanesulfonate,(1R,5R)-Rel-(9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, identity confirmation via IR and NMR spectroscopy, and quantification of key impurities. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request to ensure full traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (1R,5R)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.