Description

Endo-8-Oxabicyclo[3.2.1]Octan-3-Ol CAS NO 343963-51-9 is a high-purity, specialized bicyclic ether-alcohol compound of significant interest in advanced organic synthesis. This molecule serves as a versatile and critical chiral building block for the construction of complex pharmacologically active structures. It is primarily sought after by research institutions and pharmaceutical development companies engaged in the creation of new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) targets.
• Asymmetric Synthesis: Utilized as a precursor or auxiliary in catalytic asymmetric reactions to introduce stereochemical complexity.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs due to its rigid, three-dimensional scaffold.
• Fine Chemical Production: Used in the multi-step synthesis of specialty chemicals, agrochemicals, and other high-value compounds requiring specific stereochemistry.
• Academic & Industrial R&D: Serves as a model compound or starting material in methodological development for organic and process chemistry.

Basic Information

Product Name	Endo-8-Oxabicyclo[3.2.1]Octan-3-Ol
CAS No.	343963-51-9
Molecular Formula	C7H12O2
Molecular Weight	128.17 g/mol
Synonyms	8-Oxabicyclo[3.2.1]octan-3-ol, endo-; endo-3-Hydroxy-8-oxabicyclo[3.2.1]octane; Bicyclo[3.2.1]octan-3-ol, 8-oxa-, endo-; (1R,3S,5S)-8-Oxabicyclo[3.2.1]octan-3-ol; endo-3-Hydroxy-8-oxabicyclo[3.2.1]octane; 8-Oxabicyclo[3.2.1]octan-3-ol (endo isomer)
EINECS	Contact for details

Quality Control

Our Endo-8-Oxabicyclo[3.2.1]Octan-3-Ol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. All products undergo rigorous analytical testing, including chiral purity verification by HPLC and structural confirmation by NMR and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). The compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.