Description

4-Bromo-2-Iodo-1-Nitrobenzene is a halogenated nitroaromatic compound that serves as a versatile and critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable precursor for constructing complex molecules, particularly in the development of pharmaceuticals and functional materials. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogen and nitro functionalities into their target compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of novel drug candidates with halogenated aromatic cores.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides where the bromo and iodo substituents are crucial for biological activity.
• Material Science Research: Serves as a precursor for the development of organic electronic materials, liquid crystals, and advanced polymers.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira, Heck) due to the presence of both bromo and iodo leaving groups, allowing for sequential functionalization.
• Dye and Pigment Manufacturing: Employed in the synthesis of complex, halogenated dyes and pigments for high-performance applications.
• Academic and R&D Laboratories: A valuable reagent for methodological development in organic chemistry and for creating specialized compound libraries.

Basic Information

Product Name	4-Bromo-2-Iodo-1-Nitrobenzene
CAS No.	343864-78-8
Molecular Formula	C6H3BrINO2
Molecular Weight	327.90 g/mol
Synonyms	1-Bromo-4-iodo-2-nitrobenzene; 2-Iodo-4-bromonitrobenzene; 4-Bromo-2-iodonitrobenzene; Benzene, 1-bromo-4-iodo-2-nitro-; 4-Bromo-2-iodo-1-nitro-benzene
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Iodo-1-Nitrobenzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment ensures the material meets the stringent requirements for research and commercial synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.