Description

8-Benzyloxy-2-Chloroquinoline is a high-purity, functionalized quinoline derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular scaffold, which enables the construction of complex heterocyclic systems with tailored properties. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for antimicrobial, anti-inflammatory, or kinase inhibitor applications.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, or insecticides, leveraging the bioactivity of the quinoline core.
• Material Science Research: Serves as a precursor for organic ligands in catalysis or as a monomer for constructing specialized polymers with optoelectronic properties.
• Chemical Biology Probe Development: Employed in designing molecular probes and inhibitors for studying biological pathways and target validation.
• Academic & Contract Research: Essential for methodological studies in organic chemistry, including cross-coupling reactions and heterocycle functionalization.

Basic Information

Product Name	8-Benzyloxy-2-Chloroquinoline
CAS No.	343788-51-2
Molecular Formula	C₁₆H₁₂ClNO
Molecular Weight	269.73 g/mol
Synonyms	2-Chloro-8-(phenylmethoxy)quinoline; 8-(Benzyloxy)-2-chloroquinoline; Quinoline, 2-chloro-8-(phenylmethoxy)-; 2-Chloro-8-benzyloxyquinoline; 8-Benzyloxy-2-chloro-quinoline
EINECS	Contact for details

Quality Control

Our 8-Benzyloxy-2-Chloroquinoline is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.